Estriol - Safest Type of EstrogenIn addition, during pregnancy a woman's production of this hormone frequently jumps by as much as 1,000%, and remains elevated after the pregnancy. Although both estradiol and estrone have been found to promote cancer, due to the fact that they stimulate cell growth, estriol seems to protect against cancer, even though researchers don't yet know exactly why. They suspect it may be because it fills estrogen receptor sites in the cells, so the stronger estrogens can't use them. 
At any rate, for whatever reason, one study of 15,000 women over a forty year period, showed that the women who had the highest rates of estriol during pregnancy had the lowest rates of cancer. Specifically, those with the top 25% of estriol production during pregnancy had a 58% lower rate of breast cancer in the following forty years. One women's cancer specialist, named Dr. Lemon, came up with what he called the Estrogen Quotient(EQ), which is the ratio of estriol to the sum of the other two main estrogens, estradiol and estrone. You add the last two types together and then divide them into the total amount of the first. The higher your number the better. Estriol's Benefits
However, please remember, if using a natural progesterone cream will resolve the problem, making estrogen supplementation unnecessary, that is always the safer solution for vaginal atrophy. Further Research OpportunitiesSpecific information on the value of this hormone isn't particularly easy to find, but there are reliable sources available.Two books I've mentioned previously What Your Doctor May Not Tell You About Menopause (TM): The Breakthrough Book on Natural Hormone Balance I also found detailed information from a magazine article published by Life Extension in August 2008 titled "Estriol Its Weakness is its Strength" A third source of valuable information was this article about its benefits, by Dr. Jonathan Wright. Beware of FDA PropagandaIn January of 2008 the FDA sent warning letters to some compounding pharmacies telling them that they couldn't tell women that bio-identical hormones were safer than conventional drug hormones.They claim that the drugs are "safer" because studies have been done on them and their side effects are "known". They say that natural hormones are not FDA approved to treat menopausal symptoms. Of course the last statement is true. Since hormones are natural substances made in our bodies, there isn't a high enough profit margin for anyone to pay to get them approved by the FDA. Nevertheless, estriol is obviously safe for women, since our bodies have been making, and using, it since creation. In addition, there are absolutely no reports of adverse side effects from its use, and all the studies I'm aware of, have shown it to be beneficial. Finally, it is widely prescribed and used for the treatment of menopausal symptoms in both Europe and Japan. Since drug companies fund the FDA, in large measure, there is an obvious conflict of interest in their position. ConclusionsOf course, you will have to draw your own conclusions.But when symptoms of estrogen deficiency persist, they clearly believe this type of estrogen is the safest to supplement. Although I am not a doctor, if I should develop signs of estrogen deficiency, I would follow their advice. I trust I've been able to provide you with the information and resources you need to make a wise, and health boosting, decision as well. Return from Estriol to Estrogen
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